滋賀医科大学 分子診断病理学部門

①-4 早期胃癌と進行胃癌との関係、胃癌の進展機構:胃型、腸型のphenotypeからみた早期胃癌と進行胃癌との関係

Nishimura R, Mukaisho K, Yamamoto H, Sonoda A, Andoh A, Fujiyama Y, Hattori T, Sugihara H.
Precursor-derived versus de-novo carcinogenesis depends on lineage-specific mucin phenotypes of intramucosal gland-forming gastric neoplasms.
Histopathology. 2013, 63,616-629.  <PubMed Abstract>


Natsagdorj L, Sugihara H, Bamba M, Hattori T.
Intratumoural heterogeneity of intestinal expression reflects environmental induction and progression-related loss of induction in undifferentiated-type gastric carcinomas.
Histopathology 53 (6) : 685-97, 2008  <PubMed Abstract>


Tanaka A, Takemura-Tsukashita S, Kushima R, Sugihara H, Fujiyama Y, Hattori T.
Low-grade gastric adenomas/dysplasias: phenotypic expression, DNA ploidy pattern, and LOH at microsatellites linked to the APC gene.
Pathol Res Pract 204 (1) : 1-9, 2007  <PubMed Abstract>


九嶋亮治, 向所賢一, 塚下しづき, 彭 敦發, 杉原洋行, Michael V, Manfred S, 服部隆則
胃型分化型胃癌の分子生物学的特徴
胃と腸 38 (5) : 707-721, 2003


Tsukashita S, Kushima R, Bamba M, Nakamura E, Mukaisho K, Sugihara H, Hattori T.
Beta-catenin expression in intramucosal neoplastic lesions of the stomach. Comparative analysis of adenoma/dysplasia, adenocarcinoma and signet-ring cell carcinoma.
Oncology 64 (3) : 251-258, 2003  <PubMed Abstract>


Bamba M, Sugihara H, Kushima R, Okada K, Tsukashita S, Horinouchi M, Hattori T.
Time-dependent expression of intestinal phenotype in signet ring cell carcinomas of the human stomach.
Virchows Arch 438 (1) : 49-56, 2001  <PubMed Abstract>


Tsukashita S, Kushima R, Bamba M, Sugihara H, Hattori T.
MUC gene expression and histogenesis of adenocarcinoma of the stomach.
Int J Cancer 94 (2) : 166-170, 2001  <PubMed Abstract>


Moritani S, Kushima R, Sugihara H, Hattori T
Phenotypic characteristics of Epstein-Barr-virus-associated gastric carcinomas.
J Cancer Res Clin Oncol 122 (12) : 750-756, 1996  <PubMed Abstract>