滋賀医科大学 分子診断病理学部門

①-7 早期胃癌と進行胃癌との関係、胃癌の進展機構:ゲノム解析の方法論

Tsubosa Y, Sugihara H, Mukaisho K, Kamitani S, Peng DF, Ling ZQ, Tani T, Hattori T.
Effects of degenerate oligonucleotide-primed polymerase chain reaction amplification and labeling methods on the sensitivity and specificity of metaphase- and array-based comparative genomic hybridization.
Cancer Genet Cytogenet 158 (2) : 156-166, 2005  <PubMed Abstract>


Shiomi H, Sugihara H, Kamitani S, Tokugawa T, Tsubosa Y, Okada K, Tamura H, Tani T, Kodama M, Hattori T.
Cytogenetic heterogeneity and progression of esophageal squamous cell carcinoma.
Cancer Genet Cytogenet 147 (1) : 50-61, 2003  <PubMed Abstract>


Kamitani S, Sugihara H, Tani T, Hattori T.
Intratumoral regional variations in copy number of the chromosomal part revealed by microdissection and combined ploidy and comparative genomic hybridization analyses in esophageal squamous cell carcinoma.
Cancer Genet Cytogenet 132 (1) : 30-35, 2002  <PubMed Abstract>


Tamura H, Sugihara H, Bamba M, Tani T, Hosokawa M, Kodama M, Hattori T.
Clonal analysis of esophageal squamous cell carcinoma with intraepithelial components.
Pathobiology 69 (6) : 289-296, 2001  <PubMed Abstract>


Okada K, Sugihara H, Bamba M, Bamba T, Hattori T.
Sequential numerical changes of chromosomes 7 and 18 in diffuse-type stomach cancer cell lines: Combined comparative genomic hybridization, fluorescence in situ hybridization and ploidy analyses.
Cancer Genet Cytogenet 118 (2) : 99-107, 2000  <PubMed Abstract>


Tsujimoto H, Sugihara H, Hagiwara A, Hattori T.
Amplification of growth factor receptor genes and DNA ploidy pattern in the progression of gastric cancer.
Virchows Arch 431 (6) : 388-389, 1997  <PubMed Abstract>