滋賀医科大学 分子診断病理学部門

③ デキストラン硫酸ナトリウムによるラット実験大腸炎(荒木克夫客員准教授との共同研究)

(荒木克夫客員准教授との共同研究)


Araki Y, Bamba T, Mukaisho K, Kanauchi O, Ban H, Bamba S, Andoh A, Fujiyama Y, Hattori T, Sugihara H.
Dextran sulfate sodium administered orally is depolymerized in the stomach and induces cell cycle arrest plus apoptosis in the colon in early mouse colitis.
Oncology Reports, 28 (5) : 1597-1605, 2012 <PubMed Abstract>


Araki Y, Mukaisho K, Sugihara H, Fujiyama Y, Hattori T.
Proteus mirabilis sp. intestinal microflora grow in a dextran sulfate sodium-rich environment.
Int J Mol Med 25 (2) : 203-208, 2010 <PubMed Abstract>


Araki Y, Mukaisyo K, Sugihara H, Fujiyama Y, Hattori T.
Increased apoptosis and decreased proliferation of colonic epithelium in dextran sulfate sodium-induced colitis in mice.
Oncol Rep 24 (4) : 869-874, 2010 <PubMed Abstract>


Araki Y, Mukaisho K, Sugihara H, Fujiyama Y, Hattori T.
Detection of N-nitroso-bile acids at 285 nm in reverse-phase HPLC.
J Sep Sci 31 (15) : 2827-2830, 2008 <PubMed Abstract>


Araki Y, Mukaisho K, Sugiahra H, Hattori T.
Decomposition of dextran sulfate sodium under alkaline, acidic, high temperature and high pressure conditions.
Oncol Rep 20 (1) : 147-149, 2008 <PubMed Abstract>


Araki Y, Sugihara H, Hattori T.
Chemical depolymerization of dextran sulfate sodium – the application of size-exclusion or ion-pair liquid chromatography.
Biomed Chromatogr 21 (4) : 335-337, 2007<PubMed Abstract>


Araki Y, Kanauchi O, Sugihara H, Fujiyama Y, Hattori T.
Germinated barley foodstuff suppresses dextran sulfate experimental colitis in rats: the role of mast cells.
Int J Mol Med 19 (2) : 257-262, 2007 <PubMed Abstract>


Araki Y, Sugihara H, Hattori T.
In vitro effects of dextran sulfate sodium on a Caco-2 cell line and plausible mechanisms for dextran sulfate sodium-induced colitis.
Oncol Rep 16 (6) : 1357-1362, 2006 <PubMed Abstract>


Araki Y, Sugihara H, Hattori T.
The free radical scavengers edaravone and tempol suppress experimental dextran sulfate sodium-induced colitis in mice.
Int J Mol Med 17 (2) : 331-4, 2006 <PubMed Abstract>